Milestone

August 2015
Nanos Medical Technology (Shanghai) Co., Ltd. founded
October 2015
Suzhou Nanos Medical Instrument Co., Ltd. founded
November 2015
Suzhou Nanos Medical Manufacturing Facility built
December 2015
Passed the ISO 13485 Quality Management System

Orientation and Organization

Nanos Medical is a sino-foreign joint venture medical device manufacturer, with three founders and several VC/PE forming the board of shareholders, including Medtronic, the world's largest medical device manufacturer, Sequoia Fund.
Nanos Medical is a sino-foreign joint venture medical device manufacturer, with three founders and several VC/PE forming the board of shareholders, including Medtronic, the world's largest medical device manufacturer, Sequoia Fund.
It is also committed to be a professional commercial transformation platform, actively and continuously introducing advanced foreign medical device technology, so that new medical devices can quickly enter China, the second largest market in the world.

Nanos Medical Manufacturing Facility

· ISO 13485 Certificate

· A full set of interventional catheter and low-temperature plasma electrode tip manufacturing equipment

· Factory area of 2,000 m2 (two sites)

· Class 10,000 clean workshop of 500 m2

· Sound physical, chemical and microbiological laboratories

· Independent product test system

· Independent material unpacking, incoming inspection, packaging, quality inspection, warehouse and other areas

Core Technology and Manufacturing Process

Balloon forming
End catheter welding
UV light gluing and curing
Catheter bending curvature shaping
Branch catheter tip shaping
Stent drug spraying
Hydrophilic coating of pipes and wires
Drug stent crimping
Electric soldering iron welding
Catheter developing ring swaging
Handpiece laser marking
Luminous wire making
Guide wire welding and grinding
Wire centerless grinding
PTFE hydrophobic coating of pipes and wires
Precision welding of tungsten wire/platinoiridita wire
Sealing and packaging
Plasma welding
Product Testing Process
Straightness test of guide wireProduct sterility testingPhysical and chemical poperties testing (GC/LC)Sterility microbiological testingSafety regulationsImpedance
Balloon burst pressure testingTension test of pipes and wires Catheter luminous flux test Coating peel force testingCatheter pushability testingBalloon vacuum leak testCatheter passability testSurface friction testFracture resistance testing Catheter torquability test

Mechanism of Action of Sinuplasty

微信图片_20220801172403.png

Features

Minimally invasive

no cartilage tissue is removed

Safe

virtually no risks or complications

Effective

rapid relief of symptoms

Quick recovery

within 24 hours

Company's existing products

Nasclear Sinuplasty Catheter Set

• Sinus balloon catheter

• Sinus guiding catheter

• Sinus guide wire (luminous)

• Sinus flushing catheter

NasclearⅡ™ Sinus Balloon Dilatation System

• Integration of of guiding, flushing and balloon dilation function

• Quick and easy to use, shortening the operation time

• Greatly facilitates the operator and reduces the patient's discomfort

Naspand™ Balloon Catheter of Eustachian Tube

• The balloon has 16 sizes, up to 4.0 mm

• Better adaptability to different clinical needs

• The balloon is non-compliant, with good pressure-bearing capability

• The balloon crimp diameter is only 0.7 mm to facilitate passage through narrower diseased area

Nasnore™ Nasal Airway Stent

• 12 sizes to keep airway unobstructed

• Rapid relief of OSAS (sleep apnea syndrome)

• Easy to use with little foreign body sensation

Low-temperature plasma electrode tip products

• Plasma knife ENT series

• Plasma knife orthopedic series

• Plasma knife urology series

• Plasma knife ophthalmic series

• 9 series, a total of 36 specifications/models

1 2
Product Market Authorization
Otolaryngology Class II:
Product nameApplied inApproved in
Sinuplasty Catheter Set September 2016September 2017
Sinus Balloon Dilatation System February 2018September 2018
Balloon Catheter of Eustachian Tube August 2018October 2019
Nasal Airway Stent June 2018November 2019
Nasal Airway Stent (II) June 2020November 2020
Sinuplasty Guiding Catheter August 2021March 2022
LED Medical Endoscopic Cold Light Illuminator April 2021March 2022
Disposable RF Plasma Electrode Tip October 2021May 2022
Medical Endoscopic Camera Lens August 2021June 2022
4K Medical Endoscopic Camera System August 2021June 2022
Otolaryngology Class I:
Product nameApplied inApproved in
Nasal Introducer August 2019November 2019
Licensed Patents
SNPatent namePatent number
1 Cardiac volume reduction system201620968038.2
2 Fully compliant balloon soft angiographic catheter201621025217.9
3 Sinus balloon dilatation system201720319997.6
4 Medical dilator201730098546X
5 Ear lesion system dilating device201721478647.0
6 A dilating catheter for narrowing or atresia of the eustachian tube in otology2017 2 0275110.8
7 A special placement device for medical eustachian tube balloon dilatation catheter201920290446.0
8 A double guide wire balloon dilatation catheter201920644646.1
9 A nasolacrimal duct balloon dilatation catheter (double report)201920290441.8
10 A completely absorbable nasolacrimal stent and its delivery system201920296231.X
Licensed Patents (Continued)
SNPatent namePatent number
11 A completely absorbable eustachian tube stent and its delivery system201920296232.4
12 A balloon dilatation catheter201920551511.0
13 A sinus dilation device201920550978.3
14 A nasal airway stent201920550990.4
15 Covered metal stent for eustachian tube and delivery system for implantation201921267940.1
16 Absorbable metal stent for eustachian tube and delivery system for implantation201921269443.5
17 An endoscopic and endoscopic visible sinus dilation system201921740337.0
18 Visualization cavity expansion system with light source imaging2018 2 0250254.2
19 An absorbable stent system2020212972630
20 Endoscopic catheter, components and endoscopic balloon dilation system201921771931.6

R&D Project

·Nasal Steroid-eluting Degradable Stent (NSS)  –  Multi-center clinical trial ongoing, expected to be submitted for registration in 2023/Q2
·Super-thin Endoscopic Balloon System (SEBS)  –  Type test completed, expected to be submitted for registration in July 2022
·Rhinoscope/Laryngoscope (ENT)  –  Type test ongoing
ENT field
Double guide wire cutting balloon dilatation catheter (DWB)  –  Type test completed and submitted for registration, under review
·Neuro balloon dilatation catheter (NBC)  –  Type test completed and submitted for registration, supplement and amendment ongoing
CV field

Development and Planning

01
Enrich ear, nose and throat product line and provide all-round integrated customer solutions
02
Accelerate the introduction and development of new technology products and start the registration process in overseas markets
03
Consolidate and expand the integrated cooperation mode with universities and hospitals
04
Cooperate with the Group’s listing plan